Incidence of small abdominal aortic aneurysms rupture, impact of comorbidities and our experience with rupture risk prediction based on wall stress assessment

Biomechanical rupture risk assessment of abdominal aortic aneurysms based on a novel probabilistic rupture risk index.

A rupture risk assessment is critical to the clinical treatment of abdominal aortic aneurysm (AAA) patients. The biomechanical AAA rupture risk assessment quantitatively integrates many known AAA rupture risk factors but the variability of risk predictions due to model input uncertainties remains a challenging limitation. This study derives a probabilistic rupture risk index (PRRI). Specificall...

Commentary: Computational Biomechanics-Based Rupture Prediction of Abdominal Aortic Aneurysms.

Peak wall stress does not necessarily predict the location of rupture in abdominal aortic aneurysms.

UNLABELLED Using finite element analysis, we evaluated if the site of an aortic bleb, known to be prone to rupture, coincides with the location of peak wall stress (PWS) in a patient-specific abdominal aortic aneurysm (AAA) model. REPORT PWS was not located at the bleb site, even when stress values were estimated for different bleb wall thicknesses (0.5-2.0 mm) while the rest of the AAA wall ...

Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms

BACKGROUND Ruptured abdominal aortic aneurysms (AAAs) are the 13th leading cause of death in the United States. While AAA rupture may occur without significant warning, its risk assessment is generally based on critical values of the maximum AAA diameter (> 5 cm) and AAA-growth rate (> 0.5 cm/year). These criteria may be insufficient for reliable AAA-rupture risk assessment especially when pred...

Biomechanical prediction of abdominal aortic aneurysm rupture risk: Sensitivity analysis

Objectives: The purpose of this research is to determine the quantitative relationship between the peak wall stress of abdominal aortic aneurysm (AAA) and its clinical risk factors including its maximum diameter, asymmetry index, wall thickness and abnormal high blood pressure. Methods: The response surface experimental design with one response and four variables was used to design the experime...